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According to one study published in the journalSkin Pharmacology and Physiology, oral supplementation with collagen helped increase skin elasticity and improve skin moisture in women after just four weeks. What’s more, other research shows that collagen can help relieve joint pain and reduce symptoms of osteoarthritis, a common degenerative joint disease that is often caused by wear and tear on the joints. However, the benefits of anti-aging supplements extend way beyond the surface. They help slow certain signs of aging that may not even be visible to the naked eye. Additionally, a 2019 study in 12 men with an average age of 75 showed that supplementing with 1 gram of NR daily for 21 days increased NAD+ levels in skeletal muscle and reduced levels of inflammatory proteins in the body . Anti-aging essential oils are the major part of a homemade anti-aging serum that richly hydrates your skin as well as provides antioxidant protection.
Simply stated, CoQ10 is a super antioxidant that helps get rid of free radicals and other toxins in your body. Thus, it has the effect of promoting healthy skin and allowing your body to make as much collagen as possible. Coenzyme Q10 is an antioxidant that improves mitochondrial functioning. There is insufficient scientific evidence (at least in well-conducted studies with the right disease model mice) that coenzyme Q10 can extend lifespan. Metformin has shown to extend lifespan in various organisms, including mammals . In humans, we see that diabetics taking metformin actually live longer than healthy non-diabetics who obviously don’t take metformin .
Daily Whole Foods Multivitamin For Men And Women
It keeps your NAD+ from getting too high and messing up yoursleep-wakeand hunger cycles. The activation of many of your body’s key processes wouldn’t be possible without NAD+. This coenzyme is needed in metabolic pathways like glycolysis, ? -oxidation and oxidative phosphorylation—the process of producing significant amounts of energizing ATP.
In reality, supplementing with antioxidants, like resveratrol, curcumin, and CoQ10, can start at any point in adulthood. Hyaluronic acid binds with water and can also enhance skin hydration to reduce the appearance of dry, dull skin. Curcumin and black pepper extract are generally well tolerated.
Immune Support
You need antioxidants to successfully fight free radical damage, which includes signs of aging like wrinkles and fine lines. According to research, lavender essential oil helps your body produce three of your bodies most powerful antioxidants, glutathione, catalase and superoxide dismutase. A main jojoba oil benefit is that it can play the role of sebum and moisturize our skin and hair when our body stops doing it naturally. On the other hand, too much sebum, which happens when hormone levels are high, can result in oily skin and acne. Jojoba oil is also great at removing sticky buildup or excess oil, too; so it keeps your oil levels balanced.
Which protocols of and combinations (e.g. see caloric restriction mimetic and AMPK) with DR are effective or most effective in humans is largely unknown and is being actively researched. A geroscience field of “precision nutrigeroscience” is proposed that also considers the potential need for adjustments of nutritional interventions per individual (e.g. due to differences in genetics and age). This review will emphasize the most important topical and systemic therapeutic agents and trends in the use of invasive procedures. When you consider the fact that the amount of collagen in our bodies decreases at a quickening rate as we age, drinking supplemental collagen sounds like an excellent idea. In reality, collagen does have a handful of auspicious results in clinical studies, like the ability to increase hydration in the skin, reduce the appearance of wrinkles, and ease joint pain.
Cs Natural Drainage Ginger Oil Essential Relax Massager Liquid 10ml
While you do want to keep your face clean, scrubbing it may exacerbate existing dermatological issues, including wrinkles. “Did you know that scrubbing away at your skin can cause aging?” says Dr. Ben Johnson, MD, founder of holistic beauty brand Osmosis Pur Medical Skincare. “By over exfoliating you’re actually removing the only protective barrier that your skin has.” It probably comes as no surprise that smoking is bad for your health—as it increases your risk of cancer and other serious health issues—but not everyone realizes what a major impact it can have on your appearance. Even if you only smoke occasionally, you’re making yourself look older and sicker with every puff.
Free radicals damage the cell membrane which is composed of lipids and proteins. Their interaction results in the production of the chemical Melondialdehyde which is very harmful, contributing to another important aging process called glycation. Free radicals in small and controlled quantities are useful in everyday metabolism. They take part in several normal reactions within the body including breathing.
Two clinics in California, run by Jesse Karmazin and David C. Wright, offer $8,000 injections of plasma extracted from the blood of young people. Karmazin has not published in any peer-reviewed journal and his current study does not use a control group. The controversies over cloning are similar, except general public opinion in most countries stands in opposition to reproductive cloning. Some proponents of therapeutic cloning predict the production of whole bodies, lacking consciousness, for eventual brain transplantation. In 1991, the American Academy of Anti-Aging Medicine was formed. The American Board of Medical Specialties recognizes neither anti-aging medicine nor the A4M’s professional standing.
Not only do berries fight free radicals that cause damage to your body, they also provide other essential nutrients. Sugar does more than just rot your teeth, it’s also a major contributor to the loss of firmness in the skin, which can age you significantly. “Focus on a balanced diet with plenty of lean protein and vegetables and avoid sugar,” suggests CBD Snacks Dr. Fred Pescatore, a natural health physician. “Poor diets that are high in sugar have been linked to advanced glycation end products which cause wrinkles and loss of collagen and elastin.” Vitamin A and its derivates are also a group of agents with antioxidant effects. They can induce the biosynthesis of collagen and reduce the expression of MMP 1 .
The approach is based on parabiosis studies such as those Irina Conboy has done on mice, but Conboy says young blood does not reverse aging and that those who offer those treatments have misunderstood her research. The treatment appeared in HBO’s Silicon Valley fiction series. The ethical ramifications, if life extension becomes a possibility, are debated by bioethicists. PRPs may defend against oxidative stress and support brain health. You might have heard about Omega-3s and how great they are for your health.
All products sold on this web site are intended for adults over the age of 18 and are not to be used by children under the age of 18. Do not use more than the daily dose recommended on the label of each product. Please speak with your primary care physician before purchasing or starting the use of any supplement. A marine biologist named Dr. Luis Lubian, who was involved in an extensive study of more than 43,000 types of marine phytoplankton, has discovered one strain of phytoplankton that is extremely nutrient dense and well absorbed. The scientific name of this strain of marine phytoplankton is Nannochloropsis gaditana or Nanno for short.
Here is a list of recommended NMN supplements on the market we reviewedfor you to compare. Learn more about the vitamins, minerals and other nutrients everyone should take here. However, resveratrol is difficult to be absorbed by the gut, and the little resveratrol that ends up in the body is broken down very quickly. For example, in his book Lifespan, he mentions on page 304 that he takes NMN and resveratrol every morning, often mixed in his yogurt. ††If, for any reason, you’re not satisfied with your SeroVital purchase, simply return it within the 60-day trial period for a full refund of the purchase price.
Niagen supplements typically contain just nicotinamide riboside, but some manufacturers combine it with other ingredients like Pterostilbene, which is a polyphenol — an antioxidant that is chemically similar to resveratrol . In humans, nicotinamide riboside raised NAD+ levels, helped reduce stiffness in the aorta and lowered systolic blood pressure in adults at risk of high blood pressure . Researchers believe both oxidative stress and impaired mitochondrial function are linked to age-related brain disorders such as Alzheimer’s and Parkinson’s disease . Animal studies show that nicotinamide riboside raises blood NAD+ levels by up to 2.7 times.
If you have high blood pressure or prehypertension, limiting sodium intake to 1,500 mg per day, about 2/3 teaspoon of salt, may be helpful. Preparing your own meals at home without using a lot of processed foods or salt will allow you to control how much sodium you get. Try using less salt when cooking, and don’t add salt before you take the first bite. If you make this change slowly, you will get used to the difference in taste.
The cell regulators, such as retinols, peptides and growth factors , have direct effects on collagen metabolism and influence collagen production. Some life extensionists suggest that therapeutic cloning and stem cell research could one day provide a way to generate cells, body parts, or even entire bodies that would be genetically identical to a prospective patient. Recently, the US Department of Defense initiated a program to research the possibility of growing human body parts on mice. Complex biological structures, such as mammalian joints and limbs, have not yet been replicated. Dog and primate brain transplantation experiments were conducted in the mid-20th century but failed due to rejection and the inability to restore nerve connections. As of 2006, the implantation of bio-engineered bladders grown from patients’ own cells has proven to be a viable treatment for bladder disease.
These help to dissolve the intracellular “glue” that holds dead cells together on the skin. The use of this type of product on a Dosage de CBD facile daily basis gradually enhances the exfoliation of the epidermis. This exposes newer skin cells and can help improve appearance.
XClose dialog boxPlease log in to your account to add products to your favourites. Never be without your favourite Boots products with our international delivery options. Lavender essential Are 3000mg CBD Gummies very powerful? oil is the most used essential oil in the world … If you aren’t familiar with ginger oil, there’s no better time to … Are you looking for an essential oil that will help to boost …
It treats the underlying causes of aging and aims at alleviating any age related ailment. Its goal is to extend the healthy lifespan of humans having youthful characteristics. Today’s healthcare challenges and tomorrow’s opportunity can only be met by those who search out deeper explanations of the body processes that generate health and disease.
Supports Healthy Aging
EGCG can be consumed by drinking green tea or taking concentrated supplements. Note that this list is not exhaustive, and many other supplements may also offer anti-aging effects. Aging, which can be defined as the “time-related deterioration of the physiological functions necessary for survival and fertility,” is a process that most people would like to slow . Peppermint oil is one of the most versatile essential oils out there. Always buy oils that are 100 percent pure, therapeutic grade and organic to guarantee you are getting the highest quality products that are likely to yield the best results. Jojoba oil is the perfect anti-aging base oil to combine with essentials oils to create your own DIY anti-aging serum.
Two New Super Booster Supplements
Tru Niagen is a nicotinamide riboside supplement made by ChromaDex, available in capsule or powdered form. Providing cells with these substances can help them continue to function, repair the damage, and replicate. Cellular damage also leads to senescence, which is the end of a cell’s life cycle when cells completely stop dividing.
When she’s not researching, she’s running biohacking experiments on herself, competing with her husband at everything, or taxiing her kids to sports, not in that order. There’s plenty of research that shows that NAD+ protects cells from stress. As you age, muscle is lost and fat is gained all too easily. The secret to flipping the aging switch — so you can gain muscle and lose fat — starts with HMB. It’s not possible to obtain effective and meaningful amounts of HMB from your diet, so supplementing is the only possible way to obtain all these powerful benefits.
The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Resveratrol is a polyphenol in grapes, berries, peanuts, and red wine that may promote longevity by activating certain genes called sirtuins. It has been shown to increase the lifespan of fruit flies, yeasts, and nematodes . A number of other animal studies have shown positive results related to supplementing with both NR and NMN.
This was not the case for diabetics on other anti-diabetic drugs. GEROPROTECT® Stem Cell uses three plant-based nutrients identified by artificial intelligence to support a healthy balance of stem cell self-renewal and differentiation for optimum cell health and longevity. Live your longest, healthiest life with GEROPROTECT® Autophagy Renew, a novel formula that encourages autophagy, the natural process for recycling cellular debris that can get in the way of healthy cell function. When glucose molecules and other sugars such as fructose attach themselves to proteins, it is called glycation. The binding of sugar to protein causes cross linking of proteins. Cross linked proteins cause more damage by reacting with free radicals and other toxins to create Advanced Glycation Endproducts .
I’ve been successful in getting my name off a lot of websites, but the research, Harvard’s name, and my face are still used by companies to insinuate that I endorse their product, when I would never do that. My lab and I don’t receive any money from the sale of supplements. But this cellular reprogramming is exciting because it seems to work even once you’ve lost function of tissues. I think that this drug has the potential to be used widely, like a statin. In the future, if a molecule or a drug makes it onto the market for one particular disease, then doctors can test it on their particular disease of expertise. And, if it works there — just like the statin drugs — expand it from a small group of families with high cholesterol to the world.
They do provide easy to find links to their COA results and third party testing on their website. It is suggested you take one tablet in the morning and one in the early afternoon as a minimum. This product is not suitable for vegans and the capsule option does also contain rice flour. This why alpha lipoic acid is one of the anti-aging supplements you should not take. However, alpha lipoic acid is a strong antioxidant, and scientists have learned that antioxidants could actually accelerate aging . After all, statins inhibit the production of cholesterol, a molecule that is an important component of our cell membranes, especially of neurons and muscle cells.
Dhea Supplements
A powerful combination of synergistic ingredients formulated exclusively for women. Four studies published over the last three years reveal a partial solution. Phytonutrients are antioxidants found in fruits, veggies, and nuts.
If you are going to use a supplement, make sure you purchase it from a reputable retailer and select a brand that is certified for quality by a third party, such as U.S. The seed of the flax plant contains omega-3 and omega-6 fatty acids. Chondroitin is a part of human connective tissue found in bone and cartilage. In supplements, chondroitin sulfate typically is made from bovine trachea.
The world is changing and so is the way we view our health and well being as we age. You should also speak with your primary healthcare provider to help you choose the right supplement that’s the best and safest for you. Most curcumin supplements contain concentrated doses of curcumin plus other ingredients, like black pepper extract, to help enhance absorption.
Heart-Healthy Eating 20 foods to add to your diet right now. Additionally, the circadian rhythm regulates the release of hunger hormones. In another rodent study, NAD+ showed an influence in regulating appetite, and, by extension, even body weight. A healthy circadian rhythm, sirtuins and NAD+ are all interconnected. If either sirtuins or NAD+ get disrupted, your circadian rhythm goes haywire. Researchers demonstrated this by disrupting the circadian rhythm in mice by suppressing a specific sirtuin, which depends on NAD+ to do its thing.
Research by Sobh and Martin suggests that people buy anti-aging products to obtain a hoped-for self (e.g., keeping a youthful skin) or to avoid a feared-self (e.g., looking old). The research shows that when consumers pursue a hoped-for self, it is expectations of success that most strongly drive their motivation to use the product. The research also shows why doing badly when trying to avoid a feared self is more motivating than doing well. When product use is seen to fail it is more motivating than success when consumers seek to avoid a feared-self. Welcome to HGH.com, your online store and manufacturer of HGH supplements, bodybuilding supplements and general health supplements. Human growth hormones are natural substances in our bodies that we should all value greatly, but we probably never even think about them or hear about all the wonderful things they can do for us.
Studies show that replenishing NAD+ increases lifespan in animal models because it makes DNA repair more efficient. If your NAD+ levels are in order, your cells may be protected against both impaired mitochondrial function and oxidative stress. So, if you care about keeping your energy metabolism operating properly , an NAD+ supplement can be an effective tool for counteracting any depletion of your body’s natural levels as a result of aging. All the good food you’re eating won’t do a thing for you if your cells can’t extract energy. A high-quality NAD+ supplement can help support healthy aging, since your natural levels decline as you get older. The star of AgelessLX — HMB is produced naturally in our bodies during the metabolism of the essential amino acid leucine and has powerful effects on muscle mass, fat loss, energy and metabolism.
However, those prone to oily skin or breakouts should choose lightweight moisturizers, clarifying cleansers, and other skin care items tailored to their complexion. Despite great demand, many anti-aging products and treatments have not been proven to give lasting or major positive effects. One study found that the best performing creams reduced wrinkles by less than 10% over 12 weeks, which is not noticeable to the human eye. Another study found that cheap moisturisers were as effective as high-priced anti-wrinkle creams.
Cryonics, which began in the Sixties, is the freezing – usually in liquid nitrogen – of human beings who have been legally declared dead. “Steve Aoki, Dan Bilzerian, a giraffe and the search for eternal life”. Unknown to most, Steve is both an undeniable champion of life expansion as well as one of the most prolific campaigners for life extension. Understanding that the depth of his life’s experience is limited by time alone, in his latest album Neon Future he pens lyrics such as ‘Life has limitless variety…
Pioneering EEG test could dramatically increase early diagnosis of … Magnetic stimulation of the brain can improve episodic memory, stud… Strict lineage tracing crucial to nerve cell regeneration research,… Delta 10 THC Gummies Higher levels of education and higher income mean better health for… High dose of concentrated therapy produces several lasting benefits… Exercise increases the body’s own cannabis-like substance which red…
I didn’t know it could potentially reverse cognitive decline and protect stem cells, that’s good to know, thanks. It’s important for me to share that the Ocean’s alive founder, Ian Clark, is a sexual predator and I have personally filed a police claim against him in his hometown of Cobourg, Ontario. I know several other women who he’s tried to sexually assault, and there have been several other police claims filed against him for this reason.
Trautinger F. Mechanisms of photodamage of the skin and its functional consequences for skin ageing. Margelin D, Medaisko C, Lombard D, Picard J, Fourtanier A. Hyaluronic acid and dermatan sulfate are selectively stimulated by retinoic acid in irradiated and nonirradiated hairless mouse skin. How brain cells repair their DNA reveals ‘hot spots’ of aging and d… Weight-loss treatment prevents accumulation of lipid linked to card… Study links sleep apnea in children to increased risk of high blood…
Too much of some vitamins and minerals can be harmful, and you might be paying for supplements you don’t need. Your doctor or pharmacist can recommend brands that fit your needs. Most older people Mackenzie can get all the nutrients they need from foods. But if you aren’t sure, talk with your doctor or a registered dietitian to find out if you are missing any important vitamins or minerals.
Metformin inhibits mitochondrial function, so the mitochondria will repair and protect themselves better. Our Grapeseed Extract is a potent blend of antioxidant plant extracts that help support cardiovascular health, maintain already-healthy blood pressure levels and promote longevity. Get the antioxidant benefits of alpha-lipoic acid with the added support CBD + THC Gummies of biotin in a twice-a-day capsule form to promote liver and nerve health and protect against oxidation. Some supplements contain one or two ingredients that might extend lifespan, such as nicotinamide riboside , but the jury is still out. Most longevity supplements are based on outdated ideas of aging, such as the idea that antioxidants slow down aging.
Curcumin — the main active compound in turmeric — has been shown to possess powerful anti-aging properties, which are attributed to its potent antioxidant potential. In order to buy non-prescription medicines you must be a registered user of our site as we are obliged to record your transaction history. We also ask that you complete our questionnaire so our pharmacy team can check that this product is suitable for you to buy.
Individual vitamins and minerals that are key to an anti-aging strategy include folate, iron and zinc . Selenium is a mineral found in the diets of the world’s longest-living people. You can ensure you get enough of these nutrients with a multivitamin, with stand-alone supplements, and by eating a balanced diet.
Red bell peppers, in particular, are loaded with antioxidants. In addition to their high vitamin C content (which is necessary for collagen production!), they contain powerful antioxidants. A bell pepper’s anti-inflammatory prosperities may help protect skin from sun damage, pollution, and other toxins. You don’t have to be afraid of healthy oils in your food, and you don’t have to be afraid of them in your skincare routine, either. In fact, oil-based products can keep your skin hydrated and reduce your risk of damage.
Megavitamins Online Supplement Store Australia provides all kind of Vitamin Supplements, Iron Supplements, Nutritional Supplements, Protein Supplements, Natural Supplements, Hair loss supplements for all men, women and Kids. Dr. Ron’s Ultra-Pure was founded in 2000 to meet the needs of patients who require nutritional supplements for their health, well-being and longevity. Since there were few options available which were both 100% additive-free and free from lubricating oils such as magnesium stearate, Dr. Ron began formulating, producing and providing them for his patients. High quality nutritional supplements for weight loss, detox, cleansing and anti-aging since 1992.
Before release for sale, every batch of each food supplement is checked for purity and heavy metals at the laboratory of the Faculty of Biotechnology and Food Science in the University of Life Sciences in Wrocław, Poland. We are delighted to hear stories of their acquaintances not recognizing CBD Öl Kokosnuss them on the street, and of strangers not believing their age and asking to see ID with date of birth. Join others in easily hearing how to optimise your health like diet, fitness and mental health, from experts & personal success stories on the Biohackers Lab podcast show.
Vitamin A increases cell reproduction and stimulates collagen production. Zinc and calcium are both necessary for your health in general, but they’re also critical for the health of your skin. Zinc is essential for cell structure and tissue strength, which helps fight wrinkles and keep skin tight. Meanwhile, calcium helps with cell regeneration and cell growth, thus keeping your skin youthful and beautiful.
Supplement Appears To Boost Muscle, Mitochondria Health
Our RNA supplement contains 500 mg of ribonucleic acid in each capsule. Blueberry Extract and Pomegranate delivers the antioxidant benefits of a potent blueberry extract with the extra benefits of pomegranate. Our Decaffeinated Mega Green Tea Extract provides more of the health-promoting polyphenol EGCG than the equivalent of several cups of green tea, without the caffeine.
This spiky plant grows naturally in dry, tropical climates in Africa, Asia, Europe, and the southern and western parts of the United States. Lactoferrin assists with iron absorption and is a crucial part of your immune defense system. Colostrum, otherwise known as first milk or nature’s first food, is the first type of milk produced by mammalian mothers just before or immediately following the birth of an infant. People who have health conditions like bleeding disorders should not take resveratrol without talking to a doctor first. One reason is that there’s a compound called CD-38 that destroys NAD+, which is a good thing in the right amounts.
The market for anti-aging supplements is not very transparent. Therefore, for many products it is often difficult to understand what it actually contains. Our Scandinavian background does not allow us to accept such business practices.
This type of nutrient-density could easily be incorporated into a calorie-restricted or fasting protocol without compromising your overall nutrient intake. But even stem cells can be increased or enhanced via relatively simple dietary strategies that could be considered more natural or ancestral than a $10,000 syringe of placental, amniotic, umbilical, fat- or bone-derived stem cells. Many such strategies include food compounds that our ancestors have consumed as time-honored superfoods for thousands of years.
Hands are often one of the parts of the body that show signs of aging, from dark spots to crepey skin, soonest. For more youthful-looking skin, apply moisturizer after you wash your hands and wear gloves outside when the weather dips, says Nuytten. That steamy shower may be relaxing, but it could be sapping your skin of essential moisture, making you look older in the process. “Avoid hot showers and baths; they’ll dry out skin more than anything else,” says Caroline Nuytten, a licensed esthetician at Manhattan’s Metro Integrative Pharmacy.
You can also find omega-3’s in walnuts, flax seeds, and chia seeds. Vitamin C is also needed for the synthesis of collagen, which is the main structural protein found in skin, hair, and nails. It’s also important to hydrate the skin by drinking plenty of water and protecting the skin from oxidative damage that occurs from exposure to ultraviolet light. Preventative measures include wearing sunscreen and protective clothing. Still, the sooner you start to minimize inflammation and stress that leads to aging, the better. Most people don’t think about anti-aging supplements until they notice a few wrinkles in the mirror or feel more achy or forgetful than they used to.
Glutamate, a chemical that brain cells use to talk to other cells, causes neurons to get excited, which releases free radicals and stresses them. Being in ketosis increases the NAD+ to NADH ratio, which protects brain cells from damaging free radicals. Vitamin E is an antioxidant that protects skin cells and helps maintain moisture.
Bromelain may have an anti-inflammatory effect by changing various immune responses and pathways, especially when the immune system is already stimulated. Inflammation, which contributes to a host of conditions from arthritis to digestive diseases and more—is one of them. Morales AJ, Nolan JJ, Nelson JC, Yen SS. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. Cosmetic denervation of the muscles of facial expression with botulinum toxin.
The skin anti-aging strategies attempted to reverse the dermal and epidermal signs of photo- and chronological aging can be grouped under the following approaches . African Americans who smoke seem at higher risk of coronary heart d… GlyNAC improves multiple defects in aging to boost strength and cog… Drug testing approach uncovers effective combination for treating s… Cancer-linked mutation accelerates growth of abnormal stroke-causin… Researchers wirelessly record human brain activity during normal li…
A portion of our profits and equity is donated to nonprofits in the longevity science space, like the 501, Life Extension Advocacy Foundation . Address many important mechanisms of aging, not just one or two. Are based on real science, not anecdote, tradition or belief.
Jacob has consulted for the drug companies Medicis and Abbott. Makers of the over-the-counter creams and gels don’t have to say how much retinol their products contain, and in the short term, the products might not be as effective as tretinoin. But they do smooth out the skin and minimize the effects of sun damage, Farris says. Generally, it takes about 3 to 6 months of daily use to notice a difference. With prescription retinoids, a patient might notice smoother, more even-toned skin in as early as 6 to 8 weeks. Retinoids work by prompting surface skin cells to turn over and die rapidly, making way for new cell growth underneath.
Animal and human studies have also linked Niagen supplementation with enhanced brain health and improved metabolism. Based on the above, we pulled together the following product suggestions broken down by four of the most prominent aspects of aging – cellular health, longevity, joint health, and skin health. Some substances can help cells defend against oxidative stress and inflammation, two processes that lead to damage and premature wear and tear on our cells. For best results, always follow the recommended dosage carefully, and decrease your dose if you experience any adverse side effects or symptoms.